Pharmacogenomics (PGx) Specialties:
PGL Labs focuses on the pharmacogenomics of drug metabolizing enzymes and drug transporters, with a particular highlight of examples in which genetic variations in the metabolizing enzymes and transporters influence the pharmacokinetics and/or response of particular drugs.
Pharmacogenomics is the practice of studying genetic variations that influence individual response to drugs. Knowing whether a patient carries any of these genetic variations can help prescribers individualize drug therapy, decrease the chance for adverse drug events, and increase the effectiveness of drugs. Pharmacogenomics combines traditional pharmaceutical sciences such as biochemistry with an understanding of common DNA variations in the human genome.
The US FDA has recommended PGx consideration or package-insert labeling for more than 120 drugs with relationships to greater than 50 genes. These drugs are commonly indicated in the treatments of cancers, and cardiovascular, infectious and psychiatric diseases.
Pharmacogenomics helps you choose the best medicine and correct dose prior to prescription or whenever adjustment decisions are made. With genomic insights for internal medicine, psychiatry, cardiology, paternal, or endocrinology, you will discover the genetic factors that increase disease risk or impact treatment.
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